3,4-Dichloro-5-(difluoromethyl)picolinonitrile CAS 1805998-56-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1805998-56-4
Molecular FormulaC7H2Cl2F2N2
Molecular Weight223.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,4-Dichloro-5-(difluoromethyl)picolinonitrile CAS 1805998-56-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3,4-Dichloro-5-(difluoromethyl)picolinonitrile.

CATO supplies 3,4-Dichloro-5-(difluoromethyl)picolinonitrile (CAS 1805998-56-4), a certified reference material (molecular formula C7H2Cl2F2N2, MW 223.01 g/mol) for analytical method development and quality control.

The molecular framework of 3,4-Dichloro-5-(difluoromethyl)picolinonitrile (C7H2Cl2F2N2) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3,4-Dichloro-5-(difluoromethyl)picolinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H2Cl2F2N2
Molecular Weight223.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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