6-Methyl-2-(p-tolyl)quinoline-4-carboxylic acid CAS 18060-34-9
| CAS No. | 18060-34-9 |
| Molecular Formula | C18H15NO2 |
| Molecular Weight | 277.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 6-Methyl-2-(p-tolyl)quinoline-4-carboxylic acid (C18H15NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 277.32 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6-Methyl-2-(p-tolyl)quinoline-4-carboxylic acid (CAS 18060-34-9), molecular formula C18H15NO2 and molecular weight 277.32 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Methyl-2-(p-tolyl)quinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15NO2 |
| Molecular Weight | 277.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (1R,2R)-1-((tert-butoxycarbonyl)amino)-2-phenylcyclopropane-1-carboxylic acid (CAS 180322-86-5)
- 8-Methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid (CAS 18060-44-1)
- (1S,2S)-1-((tert-butoxycarbonyl)amino)-2-phenylcyclopropane-1-carboxylic acid (CAS 180322-79-6)
- Methyl N-Cbz-piperidine-2-carboxylate (CAS 180609-56-7)
- 1-(Tert-butyl) 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate (CAS 1219158-46-9)
- 4-({[(4-hydroxyphenyl)methyl](methyl)amino}methyl)phenol (CAS 89803-09-8)
- Tert-butyl (R)-4-(2-aminopropyl)piperazine-1-carboxylate dihydrochloride (CAS 1303975-03-2)
- Amisulpride Impurity 37 (CAS 27492-84-8)
- 3-cyclopentyl-6-hydroxy-2-sulfanyl-3,4-dihydropyrimidin-4-one (CAS 556006-93-0)
- N'-[(1E)-[2,5-Dimethyl-1-(pyrazin-2-yl)-1H-pyrrol-3-yl]methylidene]thiophene-2-carbohydrazide (CAS 866009-60-1)
- 2-Methyl-6-nitrophenol (CAS 13073-29-5)
- 2,2,2-Trifluoroethyl (4-nitrophenyl)carbamate (CAS 405-59-4)
- Abemaciclib Impurity 147 (CAS 2189739-28-2)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
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