6-Chloro-4-(difluoromethyl)-3-iodopyridin-2-amine CAS 1806069-36-2
| CAS No. | 1806069-36-2 |
| Molecular Formula | C6H4ClF2IN2 |
| Molecular Weight | 304.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Chloro-4-(difluoromethyl)-3-iodopyridin-2-amine (C6H4ClF2IN2) is characterized by a nitrile group, fluorine/chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 6-Chloro-4-(difluoromethyl)-3-iodopyridin-2-amine (CAS 1806069-36-2), a certified reference material (molecular formula C6H4ClF2IN2, MW 304.46 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-4-(difluoromethyl)-3-iodopyridin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF2IN2 |
| Molecular Weight | 304.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-Chloro-3-(difluoromethoxy)-2-iodobenzene (CAS 1261477-76-2)
- 2-Chloro-1-(difluoromethoxy)-4-iodobenzene (CAS 1261604-63-0)
- 1-Chloro-3-(difluoromethoxy)-5-iodobenzene (CAS 1261645-41-3)
- 1-Chloro-2-(difluoromethoxy)-3-iodobenzene (CAS 1261670-28-3)
- 4-Chloro-2-(difluoromethoxy)-1-iodobenzene (CAS 1261685-40-8)
- 1-Chloro-4-(difluoromethoxy)-2-iodobenzene (CAS 1261850-04-7)
- 6-Chloro-2-(difluoromethyl)-5-iodopyridin-3-amine (CAS 1803670-96-3)
- 4-Chloro-6-(difluoromethyl)-3-iodopyridin-2-amine (CAS 1804723-17-8)
Recommended Standards
- 4-Chloro-3-(difluoromethyl)-5-iodopyridin-2-amine (CAS 1805325-33-0)
- 3-Chloro-2-(difluoromethyl)-6-iodopyridin-4-amine (CAS 1806069-67-9)
- 6-Chloro-2-(difluoromethyl)-3-iodopyridin-4-amine (CAS 1805207-55-9)
- 3-Chloro-5-(difluoromethyl)-2-iodopyridin-4-amine (CAS 1806829-35-5)
- Methyl 2-acetyl-1H-benzo[d]imidazole-6-carboxylate (CAS 145126-56-3)
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