4-(Difluoromethyl)-5-nitro-6-(trifluoromethoxy)pyridine-2-sulfonamide CAS 1806162-24-2
| CAS No. | 1806162-24-2 |
| Molecular Formula | C7H4F5N3O5S |
| Molecular Weight | 337.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(Difluoromethyl)-5-nitro-6-(trifluoromethoxy)pyridine-2-sulfonamide (CAS 1806162-24-2), molecular formula C7H4F5N3O5S and molecular weight 337.18 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(Difluoromethyl)-5-nitro-6-(trifluoromethoxy)pyridine-2-sulfonamide (C7H4F5N3O5S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 337.18 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4F5N3O5S |
| Molecular Weight | 337.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-5-nitro-4-(trifluoromethoxy)pyridine-3-sulfonamide (CAS 1805082-23-8)
- 2-(Difluoromethyl)-5-nitro-3-(trifluoromethoxy)pyridine-6-sulfonamide (CAS 1806061-89-1)
- 2-(Difluoromethyl)-3-nitro-6-(trifluoromethoxy)pyridine-4-sulfonamide (CAS 1806758-50-8)
- 4-(Difluoromethyl)-5-nitro-2-(trifluoromethoxy)pyridine-3-sulfonamide (CAS 1806776-34-0)
- 1-[4-(difluoromethyl)-6-(1,3-dimethyl-1h-pyrazol-4-yl)pyrimidin-2-yl]pyrrolidine-2-carboxylic acid (CAS 1092840-98-6)
- 4-(Difluoromethyl)-6-iodo-3-methyl-2-(trifluoromethyl)pyridine (CAS 1804867-49-9)
- 4-(Difluoromethyl)-5-iodo-2-methyl-3-(trifluoromethyl)pyridine (CAS 1805536-13-3)
- 2-(Difluoromethyl)-3-iodo-4-methyl-5-(trifluoromethyl)pyridine (CAS 1806950-63-9)
Recommended Standards
- 1-((4-Iodophenyl)sulfonyl)pyrrolidine (CAS 167156-16-3)
- (1-(3-Chloro-4-fluorophenyl)-3-(4-chlorophenyl)-1H-pyrazol-4-yl)methanol (CAS 618383-28-1)
- Bis(3-(trifluoromethyl)phenyl)phosphine oxide (CAS 15929-44-9)
- (3-(2,4-Dichloro-5-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol (CAS 618383-32-7)
- 3-(Methylthio)-1-(3-phenyl-1,2,4-oxadiazol-5-yl)propan-1-amine (CAS 1041601-42-6)
- Talaporfin sodium (CAS 220201-34-3)
- 4-Phenyl-2-(2-(propan-2-ylidene)hydrazinyl)benzo[d]thiazole (CAS 1210887-45-8)
- ((3AR,7aS)-2,2-dimethyl-3a,7a-dihydrobenzo[d][1,3]dioxol-5-yl)methanol (CAS 1998128-15-6)
- Ethyl 3-[(tert-butoxy)amino]propanoate (CAS 1554968-59-0)
- Methyl 5-formyl-2-methoxybenzoate (CAS 78515-16-9)
- 1-((1S,2S)-2-(Thiophen-2-yl)cyclopropyl)ethan-1-one (CAS 1807939-46-3)
- tert-Butyl 5'-bromo-4'-chloro-3-hydroxyspiro[cyclopentane-1,3'-pyrrolo[2,3-b]pyridine]-1'(2'H)-carboxylate (CAS 2413814-86-3)
- N-(4-phenoxyphenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-amine (CAS 241488-37-9)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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