3-Methyl-1-(4-methylphenyl)piperazine Dihydrochloride hydrate CAS 180622-24-6
| CAS No. | 180622-24-6 |
| Molecular Formula | C12H18N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Methyl-1-(4-methylphenyl)piperazine Dihydrochloride hydrate (CAS 180622-24-6), molecular formula C12H18N2HClH2O and molecular weight 244.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Methyl-1-(4-methylphenyl)piperazine Dihydrochloride hydrate (C12H18N2HClH2O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 3-Methyl-1-(4-methylphenyl)piperazine Dihydrochloride hydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18N2 2*HCl H2O |
| Molecular Weight | 244.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- tert-Butyl 7-hydroxy-2-azaspiro[4.4]nonane-2-carboxylate (CAS 1319716-41-0)
- tert-Butyl (2R,3R)-2-(hydroxymethyl)-3-methylazetidine-1-carboxylate (CAS 1932231-92-9)
- 2-(Butylamino)-2-oxoethyl 5-bromonicotinate (CAS 878908-86-2)
- 2,2'-(((2R,3R,4S,5R)-2,3,5-trihydroxy-6-oxohexane-1,4-diyl)bis(oxy))diacetic acid (CAS 122569-71-5)
- 1-(tert-Butyl)-3-ethyl-1H-pyrazol-5-amine (CAS 1393891-80-9)
- Carbamic acid, N-[(1S)-2-[[(1S)-3-fluoro-2-oxo-1-(phenylmethyl)propyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, phenylmethyl ester (CAS 105608-85-3)
- 1-Bromo-4-(4-bromophenyl)naphthalene (CAS 952604-26-1)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
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