3-Fluoro-5-nitropyridin-4-ol CAS 1806294-57-4
| CAS No. | 1806294-57-4 |
| Molecular Formula | C5H3FN2O3 |
| Molecular Weight | 158.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Fluoro-5-nitropyridin-4-ol (CAS 1806294-57-4), a certified reference material (molecular formula C5H3FN2O3, MW 158.09 g/mol) for analytical method development and quality control.
The molecular framework of 3-Fluoro-5-nitropyridin-4-ol (C5H3FN2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-Fluoro-5-nitropyridin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3FN2O3 |
| Molecular Weight | 158.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 3-Fluoro-5-nitropyridin-2-ol (CAS 1033202-14-0)
- 5-Fluoro-2-hydroxy-3-nitropyridine (CAS 136888-20-5)
- 2-Fluoro-5-nitropyridin-3-ol (CAS 1394982-38-7)
- 4-Fluoro-3-hydroxy-2-nitropyridine (CAS 1609165-98-1)
- 5-Fluoro-2,4-dioxo-3,4-dihydropyrimidine-1(2H)-carbaldehyde (CAS 174283-25-1)
- 3-fluoro-5-nitropyridin-1-ium-1-olate (CAS 1803602-06-3)
- 6-Fluoro-2-nitropyridin-3-ol (CAS 1803738-78-4)
- 2-Fluoro-5-nitropyridin-4-ol (CAS 1803849-39-9)
Recommended Standards
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- 3-(4-Bromophenyl)quinazoline-2,4(1H,3H)-dithione (CAS 676154-37-3)
- 2-Methyl-4-(1-methylpiperidin-2-yl)pyridine (CAS 1352485-12-1)
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