4-Difluoromethoxy-5-fluoropicolinic acid CAS 1806315-94-5
| CAS No. | 1806315-94-5 |
| Molecular Formula | C7H4F3NO3 |
| Molecular Weight | 207.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Difluoromethoxy-5-fluoropicolinic acid.
CATO supplies 4-Difluoromethoxy-5-fluoropicolinic acid (CAS 1806315-94-5), a certified reference material (molecular formula C7H4F3NO3, MW 207.11 g/mol) for analytical method development and quality control.
The molecular framework of 4-Difluoromethoxy-5-fluoropicolinic acid (C7H4F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Difluoromethoxy-5-fluoropicolinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4F3NO3 |
| Molecular Weight | 207.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethoxy Standards
- 2-(Difluoromethoxy)-1-fluoro-3-nitrobenzene (CAS 1214326-22-3)
- 1-(Difluoromethoxy)-2-fluoro-3-nitrobenzene (CAS 1214326-24-5)
- 2-(Difluoromethoxy)-4-fluoro-1-nitrobenzene (CAS 1214329-62-0)
- 3-(Difluoromethoxy)-5-fluoronitrobenzene (CAS 1214332-99-6)
- 4-(Difluoromethoxy)-2-fluoro-1-nitrobenzene (CAS 1214336-83-0)
- 1-(Difluoromethoxy)-3-fluoro-2-nitrobenzene (CAS 1214336-89-6)
- 1-(Difluoromethoxy)-4-fluoro-2-nitrobenzene (CAS 1214349-53-7)
- 6-(Difluoromethoxy)-3-fluoropyridine-2-carboxylic acid (CAS 1214386-58-9)
Recommended Standards
- 2-Difluoromethoxy-3-fluoroisonicotinic acid (CAS 1806315-88-7)
- 6-Difluoromethoxy-5-fluoronicotinic acid (CAS 1806336-32-2)
- 4-Difluoromethoxy-6-fluoronicotinic acid (CAS 1806304-82-4)
- 3-Difluoromethoxy-5-fluoroisonicotinic acid (CAS 1806336-45-7)
- 5-Chloro-2-fluoro-4-methoxybenzoic acid (CAS 211172-72-4)
- 4-(4-Methoxybenzyl)-8-(4-nitrophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane (CAS 303151-64-6)
- (E)-3-(5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-yl)acrylic acid (CAS 1785791-91-4)
- (2-Chloro-6-(1-fluorocyclobutyl)phenyl)methanol (CAS 2097159-65-2)
- 3-Bromo-4-fluoro-N,N-dimethylbenzamide (CAS 959961-63-8)
- 2-Acetylnaphthalene (CAS 93-08-3)
- 2-Bromo-N-(5-((2-((4-fluorophenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide (CAS 392297-58-4)
- 4-Chloro-2-(chloromethyl)-1-(difluoromethoxy)benzene (CAS 1049874-11-4)
- (3,3-difluorocyclohexyl)methanamine (CAS 1379151-12-8)
- Peptide Impurity 04 (CAS 2913424-91-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com