2,3-Dichloro-5-methylanisole CAS 1806346-46-2
| CAS No. | 1806346-46-2 |
| Molecular Formula | C8H8Cl2O |
| Molecular Weight | 191.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,3-Dichloro-5-methylanisole (CAS 1806346-46-2), molecular formula C8H8Cl2O and molecular weight 191.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,3-Dichloro-5-methylanisole (C8H8Cl2O) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,3-Dichloro-5-methylanisole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2O |
| Molecular Weight | 191.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
Related Dichloro Standards
- 1,2-Dichloro-5-methoxy-3-methylbenzene (CAS 112369-07-0)
- 1,3-Dichloro-5-ethoxybenzene (CAS 120388-54-7)
- 1,3-Dichloro-5-(methoxymethyl)benzene (CAS 130625-06-8)
- (2,6-Dichloro-3-methylphenyl)methanol (CAS 1378814-84-6)
- 2,6-Dichloro-3,4-dimethylphenol (CAS 1570-67-8)
- 2,6-Dichloro-4-methylbenzenemethanol (CAS 173310-45-7)
- (4,5-Dichloro-2-methylphenyl)methanol (CAS 1785226-43-8)
- 2,3-Dichloro-4-methylbenzyl alcohol (CAS 1803779-26-1)
Recommended Standards
- (2,4-Dichloro-3-methylphenyl)methanol (CAS 1806304-20-0)
- 3,5-Dichloro-4-methylanisole (CAS 1806346-58-6)
- (3,5-Dichloro-4-methylphenyl)methanol (CAS 1806288-49-2)
- 2,5-Dichloro-3-methylbenzyl alcohol (CAS 1807180-27-3)
- 2,2'-Bis(2-oxazoline) (CAS 36697-72-0)
- Tert-butylcis-4-(4-aminocyclohexyl)piperazine-1-carboxylate (CAS 1882082-89-4)
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- Methyl 5-methyl-1H-imidazole-2-carboxylate (CAS 40253-45-0)
- Methyl 2-(1-methyl-1H-pyrazol-3-yl)acetate (CAS 863032-28-4)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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