2,5-Dichloro-3-(difluoromethoxy)anisole CAS 1806348-66-2
| CAS No. | 1806348-66-2 |
| Molecular Formula | C8H6Cl2F2O2 |
| Molecular Weight | 243.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,5-Dichloro-3-(difluoromethoxy)anisole (CAS 1806348-66-2), molecular formula C8H6Cl2F2O2 and molecular weight 243.03 g/mol, is a CATO reference standard with documented purity and traceability.
2,5-Dichloro-3-(difluoromethoxy)anisole (C8H6Cl2F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,5-Dichloro-3-(difluoromethoxy)anisole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2F2O2 |
| Molecular Weight | 243.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
- 2,5-Dichloro-4-(difluoromethoxy)anisole (CAS 1803712-00-6)
- 2,3-Dichloro-4-(difluoromethoxy)benzyl alcohol (CAS 1803713-44-1)
- 2,6-Dichloro-3-(difluoromethoxy)benzyl alcohol (CAS 1803713-50-9)
- 3,4-Dichloro-2-(difluoromethoxy)benzyl alcohol (CAS 1803714-02-4)
- 2,6-Dichloro-4-(difluoromethoxy)anisole (CAS 1803786-96-0)
- 2,4-Dichloro-5-(difluoromethoxy)benzyl alcohol (CAS 1803789-25-4)
- 2,3-Dichloro-5-(difluoromethoxy)anisole (CAS 1803817-61-9)
- 2,6-Dichloro-3-(difluoromethoxy)anisole (CAS 1803817-64-2)
Recommended Standards
- 3,4-Dichloro-2-(difluoromethoxy)anisole (CAS 1806321-35-6)
- 2,5-Dichloro-3-(difluoromethoxy)benzyl alcohol (CAS 1806350-23-1)
- 2,4-Dichloro-3-(difluoromethoxy)anisole (CAS 1806321-26-5)
- 2,4-Dichloro-3-(difluoromethoxy)benzyl alcohol (CAS 1806352-90-8)
- oxan-3-amine (CAS 120811-32-7)
- 6-Chloro-2-methylimidazo[1,2-a]pyrimidin-3-amine (CAS 1522913-13-8)
- 5-(Furan-2-yl)thiophene-2-carboxylic acid (CAS 868755-62-8)
- 2-(4-(2,4-Dinitrophenyl)piperazin-1-yl)pyrimidine (CAS 307553-49-7)
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- 2-Amino-1-(3-ethylphenyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 1094337-66-2)
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- 5-(2,3-Dihydrobenzofuran-5-yl)isoxazole-3-carboxylic acid (CAS 2104290-86-8)
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