3,4-Dichloro-2-(difluoromethoxy)benzonitrile CAS 1806349-57-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1806349-57-4
Molecular FormulaC8H3Cl2F2NO
Molecular Weight238.02 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,4-Dichloro-2-(difluoromethoxy)benzonitrile CAS 1806349-57-4 chemical structure

Description

The occurrence of 3,4-Dichloro-2-(difluoromethoxy)benzonitrile is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3,4-Dichloro-2-(difluoromethoxy)benzonitrile (CAS 1806349-57-4), molecular formula C8H3Cl2F2NO and molecular weight 238.02 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3,4-Dichloro-2-(difluoromethoxy)benzonitrile (C8H3Cl2F2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3,4-Dichloro-2-(difluoromethoxy)benzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H3Cl2F2NO
Molecular Weight238.02 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms1

Related Dichloro Standards

Recommended Standards

Why CATO?