(4,6-Difluoropyridin-3-yl)methanol CAS 1806367-95-2
| CAS No. | 1806367-95-2 |
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (4,6-Difluoropyridin-3-yl)methanol is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 145.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies (4,6-Difluoropyridin-3-yl)methanol (CAS 1806367-95-2), a certified reference material (molecular formula C6H5F2NO, MW 145.11 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoropyridin Standards
- (2,6-Difluoropyridin-4-yl)methanol (CAS 1006299-98-4)
- (2,3-Difluoropyridin-4-yl)methanol (CAS 1227579-07-8)
- (2,5-Difluoropyridin-3-yl)methanol (CAS 1227588-79-5)
- (3,6-Difluoropyridin-2-yl)methanol (CAS 1227598-08-4)
- (2,4-Difluoropyridin-3-yl)methanol (CAS 1227598-92-6)
- (5,6-Difluoropyridin-2-yl)methanol (CAS 1227601-43-5)
- (2,5-Difluoropyridin-4-yl)methanol (CAS 1227601-53-7)
- (4,5-Difluoropyridin-2-yl)methanol (CAS 1803846-94-7)
Recommended Standards
- 3-(Difluoromethyl)pyridin-4-ol (CAS 1805301-71-6)
- 1806766-03-9 3-(Difluoromethyl)-2-hydroxypyridine (CAS 1806766-03-9)
- 2-(Difluoromethyl)pyridin-3-ol (CAS 1805301-68-1)
- 4,6-Difluoro-5-methylpyrimidin-2-amine (CAS 18260-79-2)
- (2R,6S,6aS)-6-triphenylsilyloxy-1,2,4,5,6,6a-hexahydropentalen-2-ol (CAS 2410639-39-1)
- 1,3-Diphenylpropane (CAS 1081-75-0)
- 2-[(2-Chloro-4-formyl-6-methoxyphenoxy)methyl]benzonitrile (CAS 443292-46-4)
- 4-Methyl-6-morpholinoquinoline-2,3-dicarboxylic acid (CAS 866039-85-2)
- Pitavastatin Calcium 2(S,S) (CAS 254452-92-1)
- 2-Amino-3-methoxy-6-methylbenzoic acid (CAS 90321-37-2)
- 4-Iodo-N,N,1-trimethyl-1H-pyrazole-3-carboxamide (CAS 1713589-33-3)
- N-(3,4-Dichlorophenyl)-3,5-dimethylbenzene-1-carboximidamide (CAS 400086-41-1)
- (1S,2R,4S,5R)-2-((S)-Hydroxy(quinolin-4-yl)methyl)-1-(2-((2-hydroxy-1-phenylethyl)amino)-2-oxoethyl)-5-vinylquinuclidin-1-ium bromide (CAS 2937392-17-9)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
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