2-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridine-4-acetonitrile CAS 1806746-57-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1806746-57-5
Molecular FormulaC10H7F5N2O2
Molecular Weight282.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridine-4-acetonitrile CAS 1806746-57-5 chemical structure

Description

The occurrence of 2-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridine-4-acetonitrile is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridine-4-acetonitrile (CAS 1806746-57-5), a certified reference material (molecular formula C10H7F5N2O2, MW 282.17 g/mol) for analytical method development and quality control.

The molecular framework of 2-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridine-4-acetonitrile (C10H7F5N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 2-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridine-4-acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7F5N2O2
Molecular Weight282.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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