(4-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridin-2-yl)methanol CAS 1806754-88-0
| CAS No. | 1806754-88-0 |
| Molecular Formula | C9H8F5NO3 |
| Molecular Weight | 273.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 273.16 g/mol gives (4-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridin-2-yl)methanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(4-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridin-2-yl)methanol (CAS 1806754-88-0), molecular formula C9H8F5NO3 and molecular weight 273.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridin-2-yl)methanol (C9H8F5NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (4-(Difluoromethyl)-5-methoxy-3-(trifluoromethoxy)pyridin-2-yl)methanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8F5NO3 |
| Molecular Weight | 273.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-3-methoxy-6-(trifluoromethoxy)pyridine-5-methanol (CAS 1804478-89-4)
- 2-(Difluoromethyl)-6-methoxy-3-(trifluoromethoxy)pyridine-4-methanol (CAS 1804479-09-1)
- (4-(Difluoromethyl)-2-methoxy-5-(trifluoromethoxy)pyridin-3-yl)methanol (CAS 1804952-76-8)
- 2-(Difluoromethyl)-3-methoxy-6-(trifluoromethoxy)pyridine-4-methanol (CAS 1805098-80-9)
- (4-(Difluoromethyl)-6-methoxy-3-(trifluoromethoxy)pyridin-2-yl)methanol (CAS 1805099-31-3)
- 2-(Difluoromethyl)-3-methoxy-5-(trifluoromethoxy)pyridine-4-methanol (CAS 1806159-27-2)
- 2-(Difluoromethyl)-3-methoxy-5-(trifluoromethoxy)pyridine-6-methanol (CAS 1806175-60-9)
- 2-(Difluoromethyl)-4-fluoro-3-(trifluoromethyl)pyridine-5-acetic acid (CAS 1804855-77-3)
Recommended Standards
- Methyl 1-(3,4-dichlorophenyl)cyclopentane-1-carboxylate (CAS 1820705-22-3)
- (3-Aminopiperidin-1-yl)(2,5-dichlorophenyl)methanone (CAS 1831622-19-5)
- (3-Aminopiperidin-1-yl)(2,3-dichlorophenyl)methanone (CAS 1832302-82-5)
- (3-(Aminomethyl)pyrrolidin-1-yl)(2,6-dichlorophenyl)methanone (CAS 1833237-72-1)
- 6-(tert-Butyl)-1,2,3,4-tetrahydroisoquinoline (CAS 404576-42-7)
- (S)-1-Cyclopropyl-4,4-difluorobutan-1-amine (CAS 2791313-84-1)
- (R)-2-Amino-2-(2-(trifluoromethoxy)phenyl)acetic acid (CAS 1228557-53-6)
- Ethyl 2-(2-methyl-3-oxo-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)acetate (CAS 139605-39-3)
- (4,5,6,7-Tetrahydro-1h-benzo[d]imidazol-2-yl)methanamine (CAS 933693-79-9)
- 2-((Butyl(ethyl)amino)methyl)benzaldehyde (CAS 1443309-16-7)
- Hexahydropyrrolo[3,2-b]pyrrol-2(1H)-one (CAS 1422140-08-6)
- 2-((1,3,4-Thiadiazol-2-yl)oxy)acetic acid (CAS 40352-26-9)
- 1-Cyclooctyl-1H-pyrrole-2,5-dione (CAS 49692-00-4)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
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