2-Bromo-5-(difluoromethyl)pyridin-4-amine CAS 1806773-35-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-(difluoromethyl)pyridin-4-amine.

2-Bromo-5-(difluoromethyl)pyridin-4-amine (CAS 1806773-35-2), molecular formula C6H5BrF2N2 and molecular weight 223.02 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C6H5BrF2N2, 2-Bromo-5-(difluoromethyl)pyridin-4-amine contains a nitrile group, fluorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 223.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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