4,6-Diamino-3-(difluoromethyl)pyridine-2-sulfonamide CAS 1806784-90-6
| CAS No. | 1806784-90-6 |
| Molecular Formula | C6H8F2N4O2S |
| Molecular Weight | 238.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,6-Diamino-3-(difluoromethyl)pyridine-2-sulfonamide (C6H8F2N4O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4,6-Diamino-3-(difluoromethyl)pyridine-2-sulfonamide (CAS 1806784-90-6), molecular formula C6H8F2N4O2S and molecular weight 238.22 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,6-Diamino-3-(difluoromethyl)pyridine-2-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8F2N4O2S |
| Molecular Weight | 238.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Diamino Standards
- 4,5-Diamino-3-(difluoromethyl)pyridine-2-sulfonamide (CAS 1806785-08-9)
- 4,6-Diamino-5-(difluoromethyl)pyridine-3-sulfonamide (CAS 1806810-41-2)
- 2,6-Diamino-4-(difluoromethyl)pyridine-3-sulfonamide (CAS 1806864-42-5)
- 2,5-Diamino-4-(difluoromethyl)pyridine-3-sulfonamide (CAS 1806869-22-6)
- (3,5-Diamino-6-chloropyrazin-2-yl)(1H-imidazol-1-yl)methanone (CAS 76962-94-2)
- 3,4-Diamino-N-(2-(dimethylamino)ethyl)-N-methylbenzamide (CAS 1044764-35-3)
- 2,7-diamino-2-phenylheptanoic acid (CAS 878788-17-1)
- 4,6-Diamino-2-(methylthio)pyrimidine-5-sulfonic acid (CAS 53286-05-8)
Recommended Standards
- 1-(4-fluoro-3-methoxy-phenyl)hexahydropyrimidine-2,4-dione (CAS 1711316-14-1)
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- Diethyl (2-(1,3-dioxolan-2-yl)ethyl)phosphonate (CAS 17053-10-0)
- 3-Amino-5-nitrobenzo[b]thiophene-2-carboxylic acid (CAS 160041-48-5)
- (2S)-3-Methoxy-2-(methylamino)propanamide (CAS 862372-12-1)
- Ethyl 3-(phenylamino)propanoate (CAS 62750-11-2)
- 1-(4-Fluorobenzyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 874298-25-6)
- 1-(Tert-butyl)-3,6-bis(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 477845-29-7)
- 6,7-dimethyl-[1,3]thiazolo[4,5-b]quinoxalin-2-amine (CAS 749202-67-3)
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