4-Amino-5-(difluoromethyl)-3-fluoropyridin-2-ol CAS 1806792-72-2
| CAS No. | 1806792-72-2 |
| Molecular Formula | C6H5F3N2O |
| Molecular Weight | 178.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Amino-5-(difluoromethyl)-3-fluoropyridin-2-ol (CAS 1806792-72-2) is a high-purity analytical reference standard with the molecular formula C6H5F3N2O and a molecular weight of 178.11 g/mol.
4-Amino-5-(difluoromethyl)-3-fluoropyridin-2-ol (C6H5F3N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5F3N2O |
| Molecular Weight | 178.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 5-Amino-2-(trifluoromethyl)-1H-pyridin-4-one (CAS 1196153-82-8)
- 2-Amino-6-(trifluoromethyl)pyridin-3-ol (CAS 1227515-04-9)
- 2-Amino-4-hydroxy-3-(trifluoromethyl)pyridine (CAS 1227515-21-0)
- 6-Amino-2-(trifluoromethyl)pyridin-3-ol (CAS 1227515-32-3)
- 2-Amino-4-hydroxy-5-(trifluoromethyl)pyridine (CAS 1227581-73-8)
- 2-Amino-3-hydroxy-4-(trifluoromethyl)pyridine (CAS 1227581-75-0)
- 2-Amino-4-hydroxy-6-(trifluoromethyl)pyridine (CAS 1227581-77-2)
- 3-Amino-4-hydroxy-2-(trifluoromethyl)pyridine (CAS 1227581-79-4)
Recommended Standards
- 6-Amino-5-(difluoromethyl)-4-fluoropyridin-3-ol (CAS 1806792-31-3)
- 4-Amino-5-(trifluoromethyl)pyridin-2-ol (CAS 1806967-28-1)
- 4-Amino-6-(difluoromethyl)-5-fluoropyridin-2-ol (CAS 1805938-18-4)
- 6-Amino-3-(trifluoromethyl)pyridin-2(1H)-one (CAS 1806967-31-6)
- 3-(2-Chloroethyl)-6-fluoro-1H-indene (CAS 1260900-03-5)
- Benzyl ((2S)-1-(((2S)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamate (CAS 1333231-43-8)
- 1-(Bromomethyl)-1-((3-methylcyclohexyl)oxy)cyclohexane (CAS 1342557-62-3)
- 3-((1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)thio)propanenitrile (CAS 154665-03-9)
- 4-Chloro-1-((2,5-difluorophenoxy)methyl)-3-nitro-1H-pyrazole (CAS 1020724-23-5)
- 3-methyl-3H-imidazo[4,5-b]pyridine-5-carboxylic acid hydrochloride (CAS 1803605-87-9)
- N-{2-[(4-bromophenyl)sulfanyl]ethyl}-4-methoxy-N-methylbenzamide (CAS 866143-58-0)
- 5-Bromo-2,3-dimethyl-1H-indole (CAS 4583-55-5)
- 2-tert-Butylphenyl isothiocyanate (CAS 36176-33-7)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com