(6-Amino-4-(difluoromethyl)-5-fluoropyridin-2-yl)methanol CAS 1806809-55-1
| CAS No. | 1806809-55-1 |
| Molecular Formula | C7H7F3N2O |
| Molecular Weight | 192.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (6-Amino-4-(difluoromethyl)-5-fluoropyridin-2-yl)methanol.
(6-Amino-4-(difluoromethyl)-5-fluoropyridin-2-yl)methanol (CAS 1806809-55-1) is a high-purity analytical reference standard with the molecular formula C7H7F3N2O and a molecular weight of 192.14 g/mol.
The molecular framework of (6-Amino-4-(difluoromethyl)-5-fluoropyridin-2-yl)methanol (C7H7F3N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (6-Amino-4-(difluoromethyl)-5-fluoropyridin-2-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7F3N2O |
| Molecular Weight | 192.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-1-methyl-6-(trifluoromethyl)-1,2-dihydropyridin-2-one (CAS 1087789-03-4)
- 5-Amino-1-(2,2,2-trifluoroethyl)pyridin-2(1h)-one (CAS 1179038-34-6)
- 5-Amino-2-methoxy-3-(trifluoromethyl)pyridine (CAS 1211584-76-7)
- 4-Amino-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one (CAS 1219089-39-0)
- 6-Amino-2-(trifluoromethyl)pyridine-3-methanol (CAS 1227509-97-8)
- (3-Amino-5-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1227516-89-3)
- 2-Amino-5-(trifluoromethyl)pyridine-3-methanol (CAS 1227572-08-8)
- 2-Amino-5-methoxy-6-(trifluoromethyl)pyridine (CAS 1227581-89-6)
Recommended Standards
- 3-(Difluoromethyl)-5-fluoro-6-methoxypyridin-2-amine (CAS 1806793-55-4)
- (2-Amino-5-(difluoromethyl)-4-fluoropyridin-3-yl)methanol (CAS 1806809-59-5)
- 4-(Aminomethyl)-3-(difluoromethyl)-6-fluoropyridin-2-ol (CAS 1805978-29-3)
- (2-Amino-6-(difluoromethyl)-4-fluoropyridin-3-yl)methanol (CAS 1806809-67-5)
- 2-Chloro-5-(oxetan-3-yl)pyridine (CAS 1400997-64-9)
- (4R,5S)-1-Isopropyl-4,5-dimethylpyrrolidin-2-one (CAS 212577-94-1)
- (3,5-Dinitrophenyl)[6-methyl-3,4-dihydro-1(2H)-quinolinyl]methanone (CAS 1023576-74-0)
- 6-Bromo-4,5-dimethylbenzo[c][1,2,5]thiadiazole (CAS 175204-24-7)
- 3-(Benzyloxy)-4-fluoro-5-(methylthio)benzoic acid (CAS 2635937-57-2)
- 4-(4-Bromophenyl)-1-methyl-1,4-azaphosphinane 4-oxide (CAS 2685825-13-0)
- 2-Methyl-4-ethylthiazoline (CAS 4293-61-2)
- Methyl 1-(piperidine-1-carboxamido)cyclohexane-1-carboxylate (CAS 1435803-85-2)
- 3-Amino-1H-pyrazolo[4,3-b]pyridine-5-carbonitrile (CAS 1314979-27-5)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com