2-(Chloromethyl)-3-(difluoromethyl)-4,5-diiodopyridine CAS 1806822-33-2
| CAS No. | 1806822-33-2 |
| Molecular Formula | C7H4ClF2I2N |
| Molecular Weight | 429.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Chloromethyl)-3-(difluoromethyl)-4,5-diiodopyridine is closely related to a nitrile group, fluorine/chlorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(Chloromethyl)-3-(difluoromethyl)-4,5-diiodopyridine (CAS 1806822-33-2), a certified reference material (molecular formula C7H4ClF2I2N, MW 429.37 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Chloromethyl)-3-(difluoromethyl)-4,5-diiodopyridine (C7H4ClF2I2N) is characterized by a nitrile group, fluorine/chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Chloromethyl)-3-(difluoromethyl)-4,5-diiodopyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF2I2N |
| Molecular Weight | 429.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-4-(difluoromethyl)-3,5-diiodopyridine (CAS 1805254-05-0)
- 2-(Chloromethyl)-5-(difluoromethyl)-3,6-diiodopyridine (CAS 1805331-39-8)
- 2-(Chloromethyl)-6-(difluoromethyl)-3,5-diiodopyridine (CAS 1805331-45-6)
- 2-(Chloromethyl)-6-(difluoromethyl)-3,4-diiodopyridine (CAS 1806826-75-4)
- 1,4-Bis(chloromethyl)-2,5-bis(octyloxy)benzene (CAS 174230-68-3)
- 5-(Chloromethyl)-5-hydroxy-3-methylfuran-2(5H)-one (CAS 71339-41-8)
- (Chloromethyl)methylbis(pentafluorophenyl)silane (CAS 77669-65-9)
- 1-(5-(Chloromethyl)-1,3,4-thiadiazol-2-yl)-2-methyl-4-((2-phenyl-1H-indol-3-yl)methylene)-1H-imidazol-5(4H)-one (CAS 143658-86-0)
Recommended Standards
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-4-phenyl-6-(propylamino)pyrimidine-5-carbonitrile (CAS 303985-78-6)
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- 1-((Benzyloxy)methyl)-5-isopropyl-6-(phenylselanyl)pyrimidine-2,4(1H,3H)-dione (CAS 172256-10-9)
- 2,2'-(Ethane-1,2-diylbis(sulfanediyl))bis(N-(3-chlorophenyl)acetamide) (CAS 222403-73-8)
- 3-((4-Chloro-3-methylphenyl)(hydroxy)boryl)benzonitrile (CAS 872495-69-7)
- 5-(tert-Butyl)-2-chlorobenzoxazole (CAS 1027076-19-2)
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- 6-Methyl-1H-pyrazolo[3,4-b]quinolin-3-ylamine (CAS 462067-00-1)
- 6-(3,4-Dichlorophenyl)imidazo[2,1-b]thiazole (CAS 910443-26-4)
- 4-(3-((2-Hydroxyethyl)amino)butyl)phenol (CAS 1038707-62-8)
- 2-(Benzyl(2-oxocyclobutyl)amino)acetonitrile (CAS 96617-35-5)
- 5-((1-((2,6-Difluorophenyl)sulfonyl)piperidin-3-yl)methyl)-3-(pyrazin-2-yl)-1,2,4-oxadiazole (CAS 1706106-28-6)
- b-Amino-2,4-dichlorobenzenepropanol (CAS 37899-17-5)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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