4-Bromo-2-(difluoromethyl)-3-fluoro-6-iodopyridine CAS 1806828-69-2
| CAS No. | 1806828-69-2 |
| Molecular Formula | C6H2BrF3IN |
| Molecular Weight | 351.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Bromo-2-(difluoromethyl)-3-fluoro-6-iodopyridine (C6H2BrF3IN) is characterized by a nitrile group, fluorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Bromo-2-(difluoromethyl)-3-fluoro-6-iodopyridine (CAS 1806828-69-2) is a high-purity analytical reference standard with the molecular formula C6H2BrF3IN and a molecular weight of 351.89 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Bromo-2-(difluoromethyl)-3-fluoro-6-iodopyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2BrF3IN |
| Molecular Weight | 351.89 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br/I-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-4-iodo-2-(trifluoromethyl)pyridine (CAS 1025509-75-4)
- 2-Bromo-3-iodo-5-(trifluoromethyl)pyridine (CAS 1214323-90-6)
- 3-Bromo-2-iodo-6-(trifluoromethyl)pyridine (CAS 1214348-80-7)
- 3-Bromo-2-iodo-5-(trifluoromethyl)pyridine (CAS 1214383-73-9)
- 2-Bromo-4-iodo-3-(trifluoromethyl)pyridine (CAS 1227496-78-7)
- 3-Bromo-6-iodo-2-(trifluoromethyl)pyridine (CAS 1227571-57-4)
- 4-Bromo-2-iodo-5-(trifluoromethyl)pyridine (CAS 1227571-68-7)
- 4-Bromo-3-iodo-2-(trifluoromethyl)pyridine (CAS 1227571-84-7)
Recommended Standards
- 2-Bromo-6-(difluoromethyl)-4-fluoro-3-iodopyridine (CAS 1806828-53-4)
- 2-Bromo-3-(difluoromethyl)-5-fluoro-6-iodopyridine (CAS 1806903-15-0)
- 4-Bromo-5-(difluoromethyl)-2-fluoro-3-iodopyridine (CAS 1806052-87-8)
- 4-Bromo-2-(difluoromethyl)-6-fluoro-3-iodopyridine (CAS 1806903-23-0)
- 2-(5-(4-Fluorobenzyl)-3-(pyridin-4-yl)-4,5-dihydro-1H-pyrazol-1-yl)acetic acid (CAS 1001383-88-5)
- 1,6-Dimethyl-4-oxo-1,4-dihydropyrimidine-5-carbonitrile (CAS 634583-90-7)
- 5-Phenyl-1H-Tetrazole (CAS 18039-42-4)
- 2-(4-(2-Methoxyphenyl)-2,2-dimethyltetrahydro-2H-pyran-4-yl)ethan-1-amine (CAS 313692-98-7)
- 2-(tert-Butoxy)-4-cyclopropoxynicotinamide (CAS 1243286-28-3)
- 2-chloro-N-[(methylamino)carbonyl]-2-phenylacetamide (CAS 99070-51-6)
- 2-(2H-1,3-Benzodioxol-4-yl)-1-butyl-6-oxopiperidine-3-carboxylic acid (CAS 478041-17-7)
- 3,3'-Bithiophene (CAS 3172-56-3)
- 1-(Bromomethyl)-1-(3,3-dimethylbutyl)cyclopropane (CAS 1495298-35-5)
- D-Val23-Tirzepatide (CAS CATO-CPTD788911)
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