3-(Difluoromethyl)-4-nitro-5-(trifluoromethyl)pyridin-2-amine CAS 1806830-76-1
| CAS No. | 1806830-76-1 |
| Molecular Formula | C7H4F5N3O2 |
| Molecular Weight | 257.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Difluoromethyl)-4-nitro-5-(trifluoromethyl)pyridin-2-amine.
3-(Difluoromethyl)-4-nitro-5-(trifluoromethyl)pyridin-2-amine (CAS 1806830-76-1), molecular formula C7H4F5N3O2 and molecular weight 257.12 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-(Difluoromethyl)-4-nitro-5-(trifluoromethyl)pyridin-2-amine (C7H4F5N3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 257.12 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(Difluoromethyl)-4-nitro-5-(trifluoromethyl)pyridin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4F5N3O2 |
| Molecular Weight | 257.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoromethyl Standards
- 5-(Difluoromethyl)-3-nitro-2-(trifluoromethyl)pyridin-4-amine (CAS 1805021-81-1)
- 3-(Difluoromethyl)-4-nitro-6-(trifluoromethyl)pyridin-2-amine (CAS 1805218-33-0)
- 3-(Difluoromethyl)-5-nitro-6-(trifluoromethyl)pyridin-2-amine (CAS 1805997-92-5)
- 4-(Difluoromethyl)-5-nitro-3-(trifluoromethyl)pyridin-2-amine (CAS 1805998-11-1)
- 6-(Difluoromethyl)-5-nitro-3-(trifluoromethyl)pyridin-2-amine (CAS 1805998-52-0)
- 3-(Difluoromethyl)-5-nitro-2-(trifluoromethyl)pyridin-4-amine (CAS 1806890-25-4)
- 6-(Difluoromethyl)-4-hydroxy-2-(trifluoromethyl)nicotinic acid (CAS 1447806-59-8)
- 2-(Difluoromethyl)-5-hydroxy-3-(trifluoromethoxy)pyridine-4-carboxaldehyde (CAS 1803959-96-7)
Recommended Standards
- 3-Bromo-1-(4-(hydroxymethyl)-2-methylphenyl)propan-1-one (CAS 1806699-01-3)
- Ethyl 4-bromo-2,6-dimethylbenzoate (CAS 1807169-47-6)
- Ethyl 4-bromo-3-ethylbenzoate (CAS 1822660-95-6)
- 3-(2-Bromo-5-methoxybenzyl)oxetane (CAS 1823348-98-6)
- Ethyl difluoro(6-methylpyridin-2-yl)acetate (CAS 503627-69-8)
- (R)-4-Bromo-N-(quinuclidin-3-yl)benzamide (CAS 355386-88-8)
- n,n,5,6-Tetramethylthieno[2,3-d]pyrimidin-4-amine (CAS 690684-98-1)
- 2-Amino-3,3-dimethylbutanenitrile (CAS 77425-86-6)
- Dapagliflozin Impurity 137 (CAS CATO-C4X-1138137)
- 2-(2-Oxoquinolin-1(2H)-yl)acetic acid (CAS 55170-65-5)
- 2-(Chloromethyl)-4-(difluoromethyl)-3-hydroxy-5-methoxypyridine (CAS 1807001-79-1)
- 3-(2-(Ethylthio)-1H-benzo[d]imidazol-1-yl)propanoic acid (CAS 332885-93-5)
- 1,2,2,2-Tetrafluoroethyl trifluoromethyl ether (CAS 2356-62-9)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
Why CATO?
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