2-(4-Amino-6-(difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile CAS 1806842-36-3
| CAS No. | 1806842-36-3 |
| Molecular Formula | C8H7F2N3O |
| Molecular Weight | 199.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-Amino-6-(difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(4-Amino-6-(difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile (CAS 1806842-36-3), molecular formula C8H7F2N3O and molecular weight 199.16 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(4-Amino-6-(difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile (C8H7F2N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 199.16 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7F2N3O |
| Molecular Weight | 199.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 1-(2-Amino-2-oxoethyl)-5-methoxy-1H-pyrazole-3-carboxylic acid (CAS 1263207-37-9)
- 3-(5-Amino-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)propanoic acid (CAS 1339479-37-6)
- Methyl 2-(5-amino-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)acetate (CAS 1343221-17-9)
- 4-Amino-2-(difluoromethyl)-5-(hydroxymethyl)nicotinonitrile (CAS 1803671-51-3)
- 2-(6-Amino-5-(difluoromethyl)-3-hydroxypyridin-2-yl)acetonitrile (CAS 1803697-68-8)
- 2-Amino-3-(difluoromethyl)-5-methoxyisonicotinonitrile (CAS 1804454-22-5)
- 4-Amino-2-(difluoromethyl)-6-(hydroxymethyl)nicotinonitrile (CAS 1804700-22-8)
- 2-Amino-4-(difluoromethyl)-5-(hydroxymethyl)nicotinonitrile (CAS 1804975-92-5)
Recommended Standards
- 2-(2-Amino-6-(difluoromethyl)-5-hydroxypyridin-3-yl)acetonitrile (CAS 1806842-01-2)
- 4-Amino-5-(difluoromethyl)-3-(hydroxymethyl)picolinonitrile (CAS 1806843-10-6)
- 2-(4-Amino-5-(difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile (CAS 1806837-61-5)
- (1R,3S,6S)-4-oxo-5-azaspiro[2.4]Heptane-1,6-dicarboxylic acid (CAS 1868986-49-5)
- Drofenine hydrochloride (CAS 548-66-3)
- Anhydronotoptol (CAS 88206-51-3)
- 3-[(E)-2-[(3,5-Dichlorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one (CAS 320420-36-8)
- (3-Fluorophenyl)(2-(pyrrolidin-1-ylmethyl)phenyl)methanone (CAS 898774-53-3)
- 7-Methoxybenzofuran (CAS 7168-85-6)
- 2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N,N-diethylacetamide (CAS 488733-83-1)
- (4-Methylpent-3-en-1-yl)diphenylphosphine oxide (CAS 86105-38-6)
- 2-(Ethyl(methyl)amino)acetohydrazide dihydrochloride (CAS 1263377-17-8)
- 2-Bromo-N-methyl-4-nitroaniline (CAS 6911-88-2)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
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