5-(Difluoromethyl)-2-fluoro-3-(hydroxymethyl)isonicotinonitrile CAS 1806844-45-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1806844-45-0
Molecular FormulaC8H5F3N2O
Molecular Weight202.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(Difluoromethyl)-2-fluoro-3-(hydroxymethyl)isonicotinonitrile CAS 1806844-45-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 202.13 g/mol gives 5-(Difluoromethyl)-2-fluoro-3-(hydroxymethyl)isonicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-(Difluoromethyl)-2-fluoro-3-(hydroxymethyl)isonicotinonitrile (CAS 1806844-45-0) is a high-purity analytical reference standard with the molecular formula C8H5F3N2O and a molecular weight of 202.13 g/mol.

5-(Difluoromethyl)-2-fluoro-3-(hydroxymethyl)isonicotinonitrile (C8H5F3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-(Difluoromethyl)-2-fluoro-3-(hydroxymethyl)isonicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H5F3N2O
Molecular Weight202.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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