3-Bromo-6-chloro-5-(difluoromethyl)pyridin-2-amine CAS 1806895-02-2
| CAS No. | 1806895-02-2 |
| Molecular Formula | C6H4BrClF2N2 |
| Molecular Weight | 257.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Bromo-6-chloro-5-(difluoromethyl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-Bromo-6-chloro-5-(difluoromethyl)pyridin-2-amine (CAS 1806895-02-2), a certified reference material (molecular formula C6H4BrClF2N2, MW 257.46 g/mol) for analytical method development and quality control.
Structurally, 3-Bromo-6-chloro-5-(difluoromethyl)pyridin-2-amine (C6H4BrClF2N2) contains a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 257.46 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4BrClF2N2 |
| Molecular Weight | 257.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 2-Bromo-1-chloro-4-(difluoromethoxy)benzene (CAS 1000574-90-2)
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- 1-Bromo-3-chloro-5-(difluoromethoxy)benzene (CAS 1004112-67-7)
- 1-Bromo-4-chloro-2-(difluoromethoxy)benzene (CAS 1056942-37-0)
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- 1-Bromo-2-[chloro(difluoro)methoxy]benzene (CAS 112556-12-4)
- 1-Bromo-4-(chlorodifluoromethoxy)benzene (CAS 112556-13-5)
- 2-Bromo-4-chloro-1-(difluoromethoxy)benzene (CAS 1214348-81-8)
Recommended Standards
- 5-Bromo-2-chloro-3-(difluoromethyl)pyridin-4-amine (CAS 1806803-94-0)
- (R)-4-Bromo-5-chloro-1-(2,2-difluorocyclopropyl)-1H-pyrazole (CAS 2641062-80-6)
- 3-Bromo-5-chloro-2-(difluoromethyl)pyridin-4-amine (CAS 1806803-92-8)
- (S)-4-Bromo-5-chloro-1-(2,2-difluorocyclopropyl)-1H-pyrazole (CAS 2641062-81-7)
- 2-(1H-Indol-3-yl)-1-phenylethanamine (CAS 1148-06-7)
- 1-(2-Chloro-6-ethylquinolin-3-yl)ethanone (CAS 1017403-43-8)
- Sodium 2-hexyldecyl sulfate (CAS 25542-86-3)
- Tert-butyl 11,11-difluoro-2,8-diazaspiro[5.5]Undecane-2-carboxylate (CAS 1780864-45-0)
- 2-Bromo-1-(3-fluoropyridin-4-yl)ethan-1-one (CAS 845714-10-5)
- 2-Amino-n-(quinolin-8-yl)acetamide (CAS 587832-36-8)
- Massonianoside B (CAS 188300-19-8)
- 3-Chloro-2-(piperidin-4-ylmethoxy)pyridine hydrochloride (CAS 2680615-72-7)
- 2-ethyl-5-(morpholine-4-sulfonyl)aniline (CAS 1017390-48-5)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
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