2-Chloro-5-(chloromethyl)-3-(difluoromethyl)isonicotinonitrile CAS 1806930-13-1
| CAS No. | 1806930-13-1 |
| Molecular Formula | C8H4Cl2F2N2 |
| Molecular Weight | 237.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-5-(chloromethyl)-3-(difluoromethyl)isonicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Chloro-5-(chloromethyl)-3-(difluoromethyl)isonicotinonitrile (CAS 1806930-13-1), a certified reference material (molecular formula C8H4Cl2F2N2, MW 237.03 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-5-(chloromethyl)-3-(difluoromethyl)isonicotinonitrile (C8H4Cl2F2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl2F2N2 |
| Molecular Weight | 237.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-Chloro-2-(chloromethyl)-5-(difluoromethyl)nicotinonitrile (CAS 1804464-80-9)
- 2-Chloro-6-(chloromethyl)-3-(difluoromethyl)isonicotinonitrile (CAS 1804665-51-7)
- 2-Chloro-6-(chloromethyl)-5-(difluoromethyl)nicotinonitrile (CAS 1805360-95-5)
- 6-Chloro-5-(chloromethyl)-4-(difluoromethyl)picolinonitrile (CAS 1805387-32-9)
- 6-Chloro-4-(chloromethyl)-5-(difluoromethyl)picolinonitrile (CAS 1805387-50-1)
- 2-Chloro-3-(chloromethyl)-5-(difluoromethyl)isonicotinonitrile (CAS 1806929-99-6)
- 6-Chloro-5-(chloromethyl)-3-(difluoromethyl)picolinonitrile (CAS 1806968-11-5)
- 3-Chloro-4-ethoxy-5-fluorobenzoyl chloride (CAS 1017778-76-5)
Recommended Standards
- 2-(2,6-Dichloro-4-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1806894-55-2)
- (3-Bromo-1-methyl-1H-pyrazol-5-yl)dimethylphosphine oxide (CAS 2903427-64-3)
- 2-(4,6-Dichloro-3-(difluoromethyl)pyridin-2-yl)acetonitrile (CAS 1806894-43-8)
- Ethyl 2-bromo-5-fluoro-1H-imidazole-4-carboxylate (CAS 959041-07-7)
- 5-Methylisothiazole (CAS 693-97-0)
- tert-butyl (4R)-4-ethyl-2,2-dioxo-oxathiazolidine-3-carboxylate (CAS 1417287-40-1)
- 4,6-Dichloro-N-phenylpyrimidin-2-amine (CAS 28230-48-0)
- 4-Amino-1-ethyl-N-((1-methyl-1h-pyrazol-4-yl)methyl)-1h-pyrazole-3-carboxamide (CAS 1006485-61-5)
- 2-(3-Hydroxy-5-methoxyphenyl)acetic acid (CAS 367259-05-0)
- (R)-N-(Piperidin-3-yl)pyridine-4-carboxamide dihydrochloride (CAS 1286208-22-7)
- 2-Cyanoquinuclidine (CAS 90196-91-1)
- 2-((4-Fluorobenzyl)thio)-5-phenyl-1-(o-tolyl)-1H-imidazole (CAS 1207043-50-2)
- 1,5-dimethyl-1H-pyrazole-4-sulfonyl chloride (CAS 1005613-94-4)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
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