4-Cyano-2-(difluoromethyl)-5-hydroxy-3-iodopyridine CAS 1806946-67-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1806946-67-7
Molecular FormulaC7H3F2IN2O
Molecular Weight296.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Cyano-2-(difluoromethyl)-5-hydroxy-3-iodopyridine CAS 1806946-67-7 chemical structure

Description

The molecular framework of 4-Cyano-2-(difluoromethyl)-5-hydroxy-3-iodopyridine (C7H3F2IN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

4-Cyano-2-(difluoromethyl)-5-hydroxy-3-iodopyridine (CAS 1806946-67-7), molecular formula C7H3F2IN2O and molecular weight 296.01 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Cyano-2-(difluoromethyl)-5-hydroxy-3-iodopyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H3F2IN2O
Molecular Weight296.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/I-containing
Nitrogen Atoms2

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