2-(Difluoromethyl)-6-iodo-3-methylpyridine-4-carboxamide CAS 1806950-50-4
| CAS No. | 1806950-50-4 |
| Molecular Formula | C8H7F2IN2O |
| Molecular Weight | 312.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Difluoromethyl)-6-iodo-3-methylpyridine-4-carboxamide (CAS 1806950-50-4) is a high-purity analytical reference standard with the molecular formula C8H7F2IN2O and a molecular weight of 312.06 g/mol.
The molecular framework of 2-(Difluoromethyl)-6-iodo-3-methylpyridine-4-carboxamide (C8H7F2IN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7F2IN2O |
| Molecular Weight | 312.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-4-iodo-3-methylpyridine-5-carboxamide (CAS 1804868-48-1)
- 4-(Difluoromethyl)-6-iodo-3-methylpicolinamide (CAS 1805102-63-9)
- 4-(Difluoromethyl)-3-iodo-5-methylpicolinamide (CAS 1805102-71-9)
- 4-(Difluoromethyl)-5-iodo-6-methylnicotinamide (CAS 1805422-63-2)
- 2-(Difluoromethyl)-3-iodo-4-methylpyridine-6-carboxamide (CAS 1805546-81-9)
- 2-(Difluoromethyl)-5-iodo-4-methylpyridine-3-carboxamide (CAS 1805599-57-8)
- 4-(Difluoromethyl)-2-iodo-5-methylnicotinamide (CAS 1805599-71-6)
- 4-(Difluoromethyl)-3-iodo-6-methylpicolinamide (CAS 1805599-77-2)
Recommended Standards
- 2-(Difluoromethyl)-3-iodo-6-methylpyridine-5-carboxamide (CAS 1806950-43-5)
- 2-(Difluoromethyl)-5-iodo-6-methylpyridine-3-carboxamide (CAS 1806983-74-3)
- 2-(Difluoromethyl)-3-iodo-5-methylpyridine-4-carboxamide (CAS 1806859-53-9)
- 2-(Difluoromethyl)-6-iodo-5-methylpyridine-3-carboxamide (CAS 1806983-81-2)
- 4-Chloro-2-methoxyphenethyl pyrimidine-5-carboxylate (CAS 823796-36-7)
- 2-Benzylbenzene-1,3,5-triol (CAS 754215-63-9)
- 5-(4-Chlorophenyl)[1,3]thiazolo[2,3-c][1,2,4]triazole-3-thiol (CAS 610276-80-7)
- 4,4'-Difluorodiphenyliodonium chloride (CAS 1828-09-7)
- 2-(Naphthalen-1-yl)thiazolidine-4-carboxylic acid (CAS 72678-97-8)
- 1-(Dimethoxymethyl)naphthalene (CAS 33250-32-7)
- 2,2’-Diiodo-4,4’-dinitrobiphenyl (CAS 61761-98-6)
- 1-Ethanethioyl-6-fluoro-1H-benzo[d]imidazol-2(3H)-one (CAS 887904-38-3)
- 1-(2-Methoxybenzyl)-1H-imidazole-5-carboxylic acid (CAS 1439902-44-9)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
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