2-Bromo-3-(difluoromethyl)-5-methylisonicotinic acid CAS 1806993-76-9
| CAS No. | 1806993-76-9 |
| Molecular Formula | C8H6BrF2NO2 |
| Molecular Weight | 266.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Bromo-3-(difluoromethyl)-5-methylisonicotinic acid (CAS 1806993-76-9), molecular formula C8H6BrF2NO2 and molecular weight 266.04 g/mol, is a CATO reference standard with documented purity and traceability.
2-Bromo-3-(difluoromethyl)-5-methylisonicotinic acid (C8H6BrF2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 2-Bromo-3-(difluoromethyl)-5-methylisonicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6BrF2NO2 |
| Molecular Weight | 266.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-Bromo-5-(difluoromethyl)-3-methylpicolinic acid (CAS 1806915-22-9)
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- 2-Bromo-4-(difluoromethyl)-5-methylnicotinic acid (CAS 1806914-35-1)
- 4-Bromo-6-(difluoromethyl)-5-methylnicotinic acid (CAS 1806994-17-1)
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