2-Bromo-5-cyano-6-(difluoromethyl)nicotinic acid CAS 1806998-92-4
| CAS No. | 1806998-92-4 |
| Molecular Formula | C8H3BrF2N2O2 |
| Molecular Weight | 277.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Bromo-5-cyano-6-(difluoromethyl)nicotinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Bromo-5-cyano-6-(difluoromethyl)nicotinic acid (CAS 1806998-92-4), molecular formula C8H3BrF2N2O2 and molecular weight 277.02 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H3BrF2N2O2, 2-Bromo-5-cyano-6-(difluoromethyl)nicotinic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 277.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3BrF2N2O2 |
| Molecular Weight | 277.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 5-Bromo-4,7-difluoro-1H-indazole-3-carboxylic acid (CAS 1459253-81-6)
- 6-Bromo-2-cyano-5-(difluoromethyl)nicotinic acid (CAS 1804640-00-3)
- 4-Bromo-2-cyano-6-(difluoromethyl)pyridine-3-carboxylic acid (CAS 1804640-26-3)
- 2-Bromo-5-cyano-4-(difluoromethyl)nicotinic acid (CAS 1804842-45-2)
- 2-Bromo-6-cyano-4-(difluoromethyl)nicotinic acid (CAS 1804842-55-4)
- 2-Bromo-3-cyano-6-(difluoromethyl)isonicotinic acid (CAS 1805354-37-3)
- 6-Bromo-5-cyano-4-(difluoromethyl)picolinic acid (CAS 1805371-24-7)
- 4-Bromo-5-cyano-3-(difluoromethyl)picolinic acid (CAS 1805431-48-4)
Recommended Standards
- 4-Bromo-6-cyano-3-(difluoromethyl)picolinic acid (CAS 1806915-83-2)
- 2-Bromo-3-cyano-5-(difluoromethyl)isonicotinic acid (CAS 1806999-30-3)
- 6-Bromo-5-cyano-4-(difluoromethyl)nicotinic acid (CAS 1806915-18-3)
- 7-Bromo-5,6-difluoroquinoxaline-2,3(1H,4H)-dione (CAS 1820707-83-2)
- 6-Bromo-4-(4-chlorobenzyl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 1207441-63-1)
- (R)-5-Methylhydantoin (CAS 55147-68-7)
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- 4-Amino-N-(3-methoxyphenyl)benzenesulfonamide (CAS 19837-79-7)
- Ethyl 4-{5-amino-7-thia-1,9-diazatetracyclo[9.2.2.0^{2,10}.0^{4,8}]pentadeca-2(10),3,5,8-tetraene-6-amido}benzoate (CAS 728003-27-8)
- 2-Chloro-5-nitro-N-(4-(pyrazin-2-yloxy)phenyl)benzamide (CAS 647853-09-6)
- 2-(2-Iodophenyl)ethanol (CAS 26059-40-5)
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- 4-Bromo-3-cyano-2-(difluoromethyl)pyridine-6-sulfonyl chloride (CAS 1806057-36-2)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
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