4-Bromo-5-(difluoromethyl)-3-hydroxypyridine-2-sulfonyl chloride CAS 1807004-05-2

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-Bromo-5-(difluoromethyl)-3-hydroxypyridine-2-sulfonyl chloride (CAS 1807004-05-2) is a high-purity analytical reference standard with the molecular formula C6H3BrClF2NO3S and a molecular weight of 322.51 g/mol.

4-Bromo-5-(difluoromethyl)-3-hydroxypyridine-2-sulfonyl chloride (C6H3BrClF2NO3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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