4-Chloro-6-cyanopicolinoyl chloride CAS 1807136-16-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1807136-16-8
Molecular FormulaC7H2Cl2N2O
Molecular Weight201.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-6-cyanopicolinoyl chloride CAS 1807136-16-8 chemical structure

Description

The occurrence of 4-Chloro-6-cyanopicolinoyl chloride is closely related to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Chloro-6-cyanopicolinoyl chloride (CAS 1807136-16-8) is a high-purity analytical reference standard with the molecular formula C7H2Cl2N2O and a molecular weight of 201.01 g/mol.

4-Chloro-6-cyanopicolinoyl chloride (C7H2Cl2N2O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Chloro-6-cyanopicolinoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H2Cl2N2O
Molecular Weight201.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentCl-containing
Nitrogen Atoms2

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