2-(Difluoromethyl)-3-methoxy-6-methylpyridine-5-acetonitrile CAS 1807136-45-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1807136-45-3
Molecular FormulaC10H10F2N2O
Molecular Weight212.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-3-methoxy-6-methylpyridine-5-acetonitrile CAS 1807136-45-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 212.20 g/mol gives 2-(Difluoromethyl)-3-methoxy-6-methylpyridine-5-acetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-(Difluoromethyl)-3-methoxy-6-methylpyridine-5-acetonitrile (CAS 1807136-45-3), a certified reference material (molecular formula C10H10F2N2O, MW 212.20 g/mol) for analytical method development and quality control.

2-(Difluoromethyl)-3-methoxy-6-methylpyridine-5-acetonitrile (C10H10F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H10F2N2O
Molecular Weight212.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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