| CAS No. | 1807155-32-3 |
| Molecular Formula | C9H4F5IN2 |
| Molecular Weight | 362.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
The occurrence of 2-(4-(Difluoromethyl)-5-iodo-2-(trifluoromethyl)pyridin-3-yl)acetonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-(Difluoromethyl)-5-iodo-2-(trifluoromethyl)pyridin-3-yl)acetonitrile (CAS 1807155-32-3) is a high-purity analytical reference standard with the molecular formula C9H4F5IN2 and a molecular weight of 362.04 g/mol.
The molecular framework of 2-(4-(Difluoromethyl)-5-iodo-2-(trifluoromethyl)pyridin-3-yl)acetonitrile (C9H4F5IN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C9H4F5IN2 |
| Molecular Weight | 362.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |