2-(Difluoromethyl)-4-fluoro-6-methylpyridine-3-carbonyl chloride CAS 1807157-52-3

Description

Compared with other compounds in its class, the molecular weight of 223.58 g/mol gives 2-(Difluoromethyl)-4-fluoro-6-methylpyridine-3-carbonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-(Difluoromethyl)-4-fluoro-6-methylpyridine-3-carbonyl chloride (CAS 1807157-52-3), a certified reference material (molecular formula C8H5ClF3NO, MW 223.58 g/mol) for analytical method development and quality control.

The molecular framework of 2-(Difluoromethyl)-4-fluoro-6-methylpyridine-3-carbonyl chloride (C8H5ClF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(Difluoromethyl)-4-fluoro-6-methylpyridine-3-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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