2-Chloro-1-methoxy-4-methyl-3-nitro-benzene CAS 1807173-28-9
| CAS No. | 1807173-28-9 |
| Molecular Formula | C8H8ClNO3 |
| Molecular Weight | 201.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-1-methoxy-4-methyl-3-nitro-benzene (CAS 1807173-28-9) is a high-purity analytical reference standard with the molecular formula C8H8ClNO3 and a molecular weight of 201.61 g/mol.
2-Chloro-1-methoxy-4-methyl-3-nitro-benzene (C8H8ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-1-methoxy-4-methyl-3-nitro-benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO3 |
| Molecular Weight | 201.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 1-chloro-5-methoxy-2-methyl-4-nitrobenzene (CAS 100777-46-6)
- 1-Chloro-4-methoxy-2-methyl-5-nitrobenzene (CAS 101080-03-9)
- 1-Chloro-2-(methoxymethyl)-4-nitrobenzene (CAS 101513-52-4)
- 2-Chloro-4-(ethylamino)pyrimidine-5-carboxylic acid (CAS 101683-59-4)
- 3-Chloro-6-ethoxypyridine-2-carboxylic acid (CAS 1020945-92-9)
- 1-Chloro-2-ethoxy-4-nitrobenzene (CAS 102236-22-6)
- 2-(2-Chloro-6-nitrophenyl)ethan-1-ol (CAS 102493-68-5)
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Recommended Standards
- Ethyl 6-chloro-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 1805670-62-5)
- Ethyl 2-chloro-5-hydroxynicotinate (CAS 1807213-36-0)
- Ethyl 5-chloro-4-hydroxynicotinate (CAS 1805670-53-4)
- Ethyl 2-chloro-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 1807213-43-9)
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- Phenoxy-d5-acetic Acid Ethyl Ester (CAS 1189442-18-9)
- 4-(Chloromethyl)-5-ethyl-1-(2-fluorophenyl)-1h-1,2,3-triazole (CAS 1338675-28-7)
- 3-(2,3-Dichlorophenyl)pyrrolidine (CAS 1260771-31-0)
- 3,6-Dichloro-2-(difluoromethoxy)phenacyl chloride (CAS 1805125-52-3)
- (R)-5-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 103882-27-5)
- 3-((3,4-Dichlorobenzyl)thio)-N-(3,4-dichlorophenyl)thiophene-2-carboxamide (CAS 251096-88-5)
- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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