2,5-Dichloro-3-(difluoromethoxy)benzyl chloride CAS 1807184-86-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1807184-86-6
Molecular FormulaC8H5Cl3F2O
Molecular Weight261.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,5-Dichloro-3-(difluoromethoxy)benzyl chloride CAS 1807184-86-6 chemical structure

Description

2,5-Dichloro-3-(difluoromethoxy)benzyl chloride (CAS 1807184-86-6) is a high-purity analytical reference standard with the molecular formula C8H5Cl3F2O and a molecular weight of 261.48 g/mol.

Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2,5-Dichloro-3-(difluoromethoxy)benzyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 261.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,5-Dichloro-3-(difluoromethoxy)benzyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H5Cl3F2O
Molecular Weight261.48 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing

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