2-Trifluoroacetylamino-1,3-propanediol CAS 180720-85-8
| CAS No. | 180720-85-8 |
| Molecular Formula | C5H8F3NO3 |
| Molecular Weight | 187.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Trifluoroacetylamino-1,3-propanediol is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Trifluoroacetylamino-1,3-propanediol (CAS 180720-85-8), molecular formula C5H8F3NO3 and molecular weight 187.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Trifluoroacetylamino-1,3-propanediol (C5H8F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Trifluoroacetylamino-1,3-propanediol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H8F3NO3 |
| Molecular Weight | 187.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoroacetylamino Standards
Recommended Standards
- 2-Amino-6-(trifluoromethyl)isonicotinonitrile (CAS 1807158-83-3)
- 6-(Trifluoromethyl)-2H-pyrazolo[4,3-b]pyridine (CAS 1822712-61-7)
- 6-Amino-4-(trifluoromethyl)picolinonitrile (CAS 1807004-79-0)
- 6-(Trifluoromethyl)-2H-pyrazolo[4,3-c]pyridine (CAS 1872431-71-4)
- 4-Chloro-5-((ethylthio)methyl)isoxazol-3(2H)-one (CAS 88918-28-9)
- 4-(4-Methylpiperazinomethyl)-2-thiomethylbenzophenone (CAS 898783-55-6)
- 4-Bromo-2-fluoro-1-propoxybenzene (CAS 127326-77-6)
- Exo-3-benzyl-3-azabicyclo[3.1.1]heptan-6-amine dihydrochloride (CAS 2306249-56-7)
- 2-(Pyridin-4-yl)propane-1,3-diol (CAS 102877-55-4)
- 4-((2,4-Dimethylphenoxy)methyl)thiophene-2-carbaldehyde (CAS 869950-34-5)
- 3-Deoxyaconitine (CAS 3175-95-9)
- 4-Chloro-N,N-diisopropyl-3-nitrobenzamide (CAS 352443-08-4)
- 2-(4-Chloro-1H-benzo[d]imidazol-2-yl)ethanamine (CAS 4499-10-9)
- Neuropeptide S (human) (CAS 412938-67-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com