2-Bromo-4-chloro-5-fluorophenacyl chloride CAS 1807224-33-4
| CAS No. | 1807224-33-4 |
| Molecular Formula | C8H4BrCl2FO |
| Molecular Weight | 285.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Bromo-4-chloro-5-fluorophenacyl chloride (C8H4BrCl2FO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Bromo-4-chloro-5-fluorophenacyl chloride (CAS 1807224-33-4) is a high-purity analytical reference standard with the molecular formula C8H4BrCl2FO and a molecular weight of 285.93 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Bromo-4-chloro-5-fluorophenacyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4BrCl2FO |
| Molecular Weight | 285.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- (3-Bromo-5-morpholinophenyl)boronic acid (CAS 1256355-10-8)
- 2-Bromo-6-chloro-4-fluorophenacyl chloride (CAS 1804382-56-6)
- 5-Bromo-3-chloro-2-fluorophenacyl chloride (CAS 1804382-66-8)
- 2-Bromo-3-chloro-5-fluorophenacyl chloride (CAS 1805518-60-8)
- 2-Bromo-5-chloro-3-fluorophenacyl chloride (CAS 1805518-62-0)
- 3-Bromo-2-chloro-5-fluorophenacyl chloride (CAS 1805518-64-2)
- 3-Bromo-4-chloro-5-fluorophenacyl chloride (CAS 1805576-12-8)
- 4-Bromo-2-chloro-6-fluorophenacyl chloride (CAS 1805576-14-0)
Recommended Standards
- 3-Bromo-5-chloro-4-fluorophenacyl chloride (CAS 1807036-60-7)
- (2-Bromo-4-morpholinophenyl)boronic acid (CAS 2225171-96-8)
- 4-Bromo-3-chloro-5-fluorophenacyl chloride (CAS 1806971-70-9)
- (3-((3-Bromopropyl)carbamoyl)phenyl)boronic acid (CAS 850567-42-9)
- Tert-butyl ((3aS,7aR)-hexahydropyrano[3,4-c]pyrrol-3a(4H)-yl)carbamate (CAS 1037368-67-4)
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- 3-((4-Methylcyclohexyl)amino)propan-1-ol (CAS 1042611-38-0)
- 3-(4-(1h-Pyrazol-1-yl)phenyl)-6-chloropyridazine (CAS 1175632-86-6)
- 6-Bromo-5-iodopyridin-3-ol (CAS 697300-70-2)
- 3437-95-4 2-Iodothiophene Thiophene, 2-iodo- EINECS 222-342-1 alpha-Iodothiophene NSC 1082 2-Thienyl iodide (CAS 3437-95-4)
- Henicosa-2,4-diynoic acid (CAS 69288-33-1)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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