4-bromo-2-(methoxymethyl)-2H-1,2,3-triazole CAS 180723-33-5

Purity 97%+In StockPharmaceutical Standards
CAS No.180723-33-5
Molecular FormulaC4H6BrN3O
Molecular Weight192.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-bromo-2-(methoxymethyl)-2H-1,2,3-triazole CAS 180723-33-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-bromo-2-(methoxymethyl)-2H-1,2,3-triazole.

4-bromo-2-(methoxymethyl)-2H-1,2,3-triazole (CAS 180723-33-5), molecular formula C4H6BrN3O and molecular weight 192.01 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-bromo-2-(methoxymethyl)-2H-1,2,3-triazole (C4H6BrN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC4H6BrN3O
Molecular Weight192.01 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2008
Halogen ContentBr-containing
Nitrogen Atoms3

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