4-Chloro-5-fluoro-2-methylbenzonitrile CAS 1807236-92-5

Description

The occurrence of 4-Chloro-5-fluoro-2-methylbenzonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Chloro-5-fluoro-2-methylbenzonitrile (CAS 1807236-92-5) is a high-purity analytical reference standard with the molecular formula C8H5ClFNC2H4 and a molecular weight of 197.64 g/mol.

4-Chloro-5-fluoro-2-methylbenzonitrile (C8H5ClFNC2H4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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