4-Chloro-6-fluoropicolinonitrile CAS 1807267-53-3
| CAS No. | 1807267-53-3 |
| Molecular Formula | C6H2ClFN2 |
| Molecular Weight | 156.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Chloro-6-fluoropicolinonitrile (CAS 1807267-53-3), a certified reference material (molecular formula C6H2ClFN2, MW 156.54 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-6-fluoropicolinonitrile (C6H2ClFN2) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-6-fluoropicolinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H2ClFN2 |
| Molecular Weight | 156.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-5-fluoronicotinonitrile (CAS 1009334-65-9)
- 2-Chloro-4-fluoronicotinonitrile (CAS 1054552-27-0)
- 2-Chloro-5-fluoroisonicotinonitrile (CAS 1057319-20-6)
- 4-Chloro-3-fluoropicolinonitrile (CAS 1155847-43-0)
- 3-Chloro-6-fluoropicolinonitrile (CAS 1207609-53-7)
- 6-Chloro-5-fluoropicolinonitrile (CAS 1256811-91-2)
- 5-Chloro-6-fluoronicotinonitrile (CAS 1256812-15-3)
- 6-Chloro-4-fluoronicotinonitrile (CAS 1256820-16-2)
Recommended Standards
- 5-Chloro-2-fluoronicotinonitrile (CAS 1807007-21-1)
- 2-Chloro-6-fluoroisonicotinonitrile (CAS 1807272-13-4)
- 4-Chloro-6-fluoronicotinonitrile (CAS 1805572-90-0)
- 2-Chloro-4-ethynyl-5-fluoropyrimidine (CAS 2445786-25-2)
- 1-(5-(Chloromethyl)isoxazol-3-yl)ethanone (CAS 93422-80-1)
- 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile (CAS 1150561-70-8)
- (4S)-Hydroxy-3-methyl-2-(2-propynyl)-2-cyclopentene-1-one (CAS 77087-34-4)
- 2-Thiophen-2-yl-benzo[h]chromen-4-one (CAS 14756-28-6)
- methoxy(propan-2-ylidene)amine (CAS 3376-35-0)
- (3S,5R)-5-(Hydroxymethyl)pyrrolidin-3-ol (CAS 825644-11-9)
- Ethyl 1-(6-(trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylate (CAS 1089330-56-2)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-6-methoxychroman-4-one (CAS 136498-37-8)
- 2-(4-((Trifluoromethyl)thio)phenyl)acetaldehyde (CAS 111991-23-2)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com