N-(3-Chloro-2-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine CAS 1807546-70-8
| CAS No. | 1807546-70-8 |
| Molecular Formula | C18H16Cl2FN3O2 |
| Molecular Weight | 396.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-(3-Chloro-2-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-(3-Chloro-2-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine (CAS 1807546-70-8) is a high-purity analytical reference standard with the molecular formula C18H16Cl2FN3O2 and a molecular weight of 396.24 g/mol.
N-(3-Chloro-2-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine (C18H16Cl2FN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16Cl2FN3O2 |
| Molecular Weight | 396.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 2-Chloro-4,5-dibromoiodobenzene (CAS 1263377-41-8)
- 3-Chloro-N-(3-chloro-4-(pyrimidin-2-yloxy)phenyl)benzenesulfonamide (CAS 823782-55-4)
- 4-Chloro-N-(3-chloro-4-(pyrimidin-2-yloxy)phenyl)benzenesulfonamide (CAS 338413-28-8)
- 4-Chloro-5-((2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)amino)-2-ethylpyridazin-3(2H)-one (CAS 320421-66-7)
- 3-Chloro-7-(chlorodifluoromethyl)-2-methyl-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine (CAS 439097-18-4)
- 3-Chloro-4,5-diiodo-6-methoxypyridazine (CAS 1375303-14-2)
- 2-Chloro-4,5-diiodo-6-methoxypyrimidine (CAS 159585-09-8)
- 2-Chloro-1,3-bis(3,4-dichlorophenyl)propane-1,3-dione (CAS 937602-36-3)
Recommended Standards
- tert-Butyl 4-iodo-6-phenylpyridin-3-ylcarbamate (CAS 941271-13-2)
- 2-(2-(3-Bromobenzylidene)hydrazinyl)-N-(naphthalen-1-yl)-2-oxoacetamide (CAS 331264-78-9)
- Ethyl 2-amino-4-(2,6-dichlorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carboxylate (CAS 317840-11-2)
- 2-[({[2,4-dichloro-5-(2-ethoxy-2-oxoethoxy)phenyl]carbamoyl}methyl)sulfanyl]acetic acid (CAS 339014-99-2)
- 1-(2-Bromo-5-fluoropyridin-4-yl)ethan-1-ol (CAS 1114523-54-4)
- 3-Pyridine-methanol-d (CAS 258854-74-9)
- 1-Methyl-4-(4-Methylhepta-1,6-Dien-4-Yl)Benzene (CAS 927833-56-5)
- N-benzyl-4-bromoaniline (CAS 2879-83-6)
- 2,5-Difluoro-4-nitroanisole (CAS 66684-63-7)
- Methyl 3-fluoro-4-methoxy-2-(methylthio)benzoate (CAS 2635937-28-7)
- (R)-Methyl 2-(((benzyloxy)carbonyl)amino)-2-(4-oxocyclohexyl)acetate (CAS 1384268-84-1)
- 14,15-Dehydroleukotrieneb4 (CAS 114616-11-4)
- Ethyl 2-(5-methyl-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)acetate (CAS 1160246-31-0)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com