trans-3-(3-chloro-4-fluorophenyl)cyclobutan-1-amine hydrochloride CAS 1807885-00-2
| CAS No. | 1807885-00-2 |
| Molecular Formula | C10H11ClFN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of trans-3-(3-chloro-4-fluorophenyl)cyclobutan-1-amine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
trans-3-(3-chloro-4-fluorophenyl)cyclobutan-1-amine hydrochloride (CAS 1807885-00-2), molecular formula C10H11ClFNHCl and molecular weight 236.11 g/mol, is a CATO reference standard with documented purity and traceability.
trans-3-(3-chloro-4-fluorophenyl)cyclobutan-1-amine hydrochloride (C10H11ClFNHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), trans-3-(3-chloro-4-fluorophenyl)cyclobutan-1-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClFN HCl |
| Molecular Weight | 236.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 3-[(2,5-Dimethylphenyl)methyl]-7-(3-fluorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1105226-86-5)
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- (4,5-Dichloro-6-oxo-1,6-dihydropyridazin-1-yl)methyl 2-chlorobenzoate (CAS 178211-07-9)
- n-Methyl-9h-fluoren-9-amine (CAS 38359-28-3)
- 1-Fluoro-2-(methylsulfinyl)benzene (CAS 61122-88-1)
- N-ethyl-1-(thiophen-2-yl)cyclohexan-1-amine (CAS 101589-62-2)
- 2,5-Di-tert-butylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 626223-27-6)
- 2-(4-Bromophenyl)-5-methyloxazole-4-carboxylic acid (CAS 355020-56-3)
- 4-Ethylpyrrolo[1,2-a]pyrazine (CAS 158945-92-7)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
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