(1R,3r)-3-(2-fluorophenyl)cyclobutan-1-amine CAS 1808068-70-3
| CAS No. | 1808068-70-3 |
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (1R,3r)-3-(2-fluorophenyl)cyclobutan-1-amine.
CATO supplies (1R,3r)-3-(2-fluorophenyl)cyclobutan-1-amine (CAS 1808068-70-3), a certified reference material (molecular formula C10H12FN, MW 165.21 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H12FN, (1R,3r)-3-(2-fluorophenyl)cyclobutan-1-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 165.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (1R,3r)-3-(2-fluorophenyl)cyclobutan-1-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3-Isothiocyanatophenyl)methanol (CAS 179549-74-7)
- (R)-5-fluoro-1,2,3,4-tetrahydronaphthalen-2-amine (CAS 181874-06-6)
- 1-(3-Fluorophenyl)cyclobutanamine (CAS 179411-86-0)
- 2-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1824337-84-9)
- 1,2-Bis(4'-phenoxyphenyl)-1,1,2,2-tetrafluoroethane (CAS 149963-10-0)
- 4-Amino-1,3-dihydro-2H-inden-2-one (CAS 1366737-66-7)
- 3-[(Methylamino)sulphonyl]benzoic Acid (CAS 35623-11-1)
- (S)-2-Amino-2-(2-(trifluoromethoxy)phenyl)acetic acid (CAS 1228547-92-9)
- 6-Chloro-N4-(2-ethoxyphenyl)pyrimidine-2,4-diamine (CAS 93003-22-6)
- (S)-3-amino-4-(2-carboxyethylamino)-4-oxobutanoic acid 89156-89-8 H-Asp-Beta-Ala-OH (CAS 89156-89-8)
- 3-Amino-4-methylheptanoic acid (CAS 204191-41-3)
- 3-(2-Methoxynaphthalen-1-yl)prop-2-en-1-amine (CAS 1344860-22-5)
- Methyl 3-(methylsulfonamido)-5-nitrobenzoate (CAS 695216-00-3)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
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