((2R,3S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-3-yl)methanol CAS 1808406-93-0
| CAS No. | 1808406-93-0 |
| Molecular Formula | C13H14F4O2 |
| Molecular Weight | 278.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 278.24 g/mol gives ((2R,3S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-3-yl)methanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies ((2R,3S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-3-yl)methanol (CAS 1808406-93-0), a certified reference material (molecular formula C13H14F4O2, MW 278.24 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, ((2R,3S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-3-yl)methanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), ((2R,3S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-3-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14F4O2 |
| Molecular Weight | 278.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Recommended Standards
- 4-Ethoxy-1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (CAS 1707372-60-8)
- 2-(2,4-Dinitrophenylthio)pyrimidine (CAS 66474-53-1)
- (2-(4-Fluoro-3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-3-yl)methanol (CAS 1555653-27-4)
- 3-(2-Amino-phenylamino)-2-cyano-acrylic acid ethyl ester (CAS 21025-47-8)
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