3-Chloro-4-methoxyphenol CAS 18093-12-4
| CAS No. | 18093-12-4 |
| Molecular Formula | C7H7ClO2 |
| Molecular Weight | 158.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-4-methoxyphenol.
CATO supplies 3-Chloro-4-methoxyphenol (CAS 18093-12-4), a certified reference material (molecular formula C7H7ClO2, MW 158.58 g/mol) for analytical method development and quality control.
Structurally, 3-Chloro-4-methoxyphenol (C7H7ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 158.58 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Chloro-4-methoxyphenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7ClO2 |
| Molecular Weight | 158.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 2-Chloro-4-(hydroxymethyl)phenol (CAS 105960-29-0)
- 2-Chloro-1-(furan-2-yl)propan-1-one (CAS 106430-52-8)
- 3-Chloro-2-(hydroxymethyl)phenol (CAS 1094627-55-0)
- 4-Chloro-3-hydroxybenzyl alcohol (CAS 1261598-26-8)
- 2-Chloro-1-(4-methylfuran-2-yl)ethanone (CAS 133674-52-9)
- 2-Chloro-1-(3-methylfuran-2-yl)ethan-1-one (CAS 1502390-71-7)
- 2-Chloro-1-(2-methylfuran-3-yl)ethan-1-one (CAS 1543126-21-1)
- 3-Chloro-4-(hydroxymethyl)phenol (CAS 171569-42-9)
Recommended Standards
- 1-fluorocyclopropanesulfonyl chloride (CAS 1780549-34-9)
- 2-Chloro-4-methoxyphenol (CAS 18113-03-6)
- 2-Chloro-5-methoxyphenol (CAS 18113-04-7)
- 3-(5-Chlorofuran-2-yl)prop-2-en-1-ol (CAS 1563267-69-5)
- (4-Chlorophenyl)(1-methyl-1h-pyrazol-3-yl)methanamine (CAS 1432680-19-7)
- N-Methylthiophen-2-amine hydrochloride (CAS 1071540-99-2)
- (E)-5-chloro-1,3-dimethyl-1H-pyrazole-4-carbaldehyde O-(2,6-difluorobenzoyl) oxime (CAS 956797-71-0)
- Allyl 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-1H-1,2,3-triazole-4-carboxylate (CAS 311787-20-9)
- 2-(5-carbamoyl-1H-pyrrole-3-sulfonamido)acetic acid (CAS 1354961-61-7)
- 2-Keto-<SC>D</SC>-gluconate hemicalcium salt hydrate (CAS 1040352-40-6)
- N1-methyl-N1-(1-(pyrazin-2-yl)ethyl)ethane-1,2-diamine (CAS 1342041-02-4)
- NVP-231 (CAS 362003-83-6)
- 5-Methyl-2-propyl-1H-pyrazol-3(2H)-one (CAS 63779-49-7)
- Peptide 438 (CAS CATO-CPTD788438)
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