Methyl 5-fluoro-3,4-dimethoxy-2-methylbenzoate CAS 1809337-17-4
| CAS No. | 1809337-17-4 |
| Molecular Formula | C11H13FO4 |
| Molecular Weight | 228.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 5-fluoro-3,4-dimethoxy-2-methylbenzoate.
CATO supplies Methyl 5-fluoro-3,4-dimethoxy-2-methylbenzoate (CAS 1809337-17-4), a certified reference material (molecular formula C11H13FO4, MW 228.22 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 5-fluoro-3,4-dimethoxy-2-methylbenzoate (C11H13FO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-fluoro-3,4-dimethoxy-2-methylbenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13FO4 |
| Molecular Weight | 228.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Methyl Standards
- Ethyl 2-(2-fluoro-3-methoxyphenyl)-2-hydroxyacetate (CAS 1151564-10-1)
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- 2-Fluoro-N-(3-methoxypropyl)-6-nitroaniline (CAS 1233955-12-8)
- 4-Fluoro-N-(3-methoxypropyl)-2-nitroaniline (CAS 1233958-30-9)
- Ethyl 6-fluoro-2,3-dimethoxybenzoate (CAS 1260651-11-3)
- 4-Fluoro-3-[(2-methoxyethoxy)methyl]benzoic acid (CAS 1341974-27-3)
- Ethyl 2-fluoro-3,6-dimethoxybenzoate (CAS 1352306-33-2)
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Recommended Standards
- Ethyl 2-fluoro-3,4-dimethoxybenzoate (CAS 1806390-89-5)
- 2-Pyrazinecarboxylic acid, 4-(fluoromethyl)-4,5-dihydro-5-oxo-, 1,1-dimethylethyl ester (CAS 1956306-79-8)
- diethyl p-tolylphosphonate (CAS 1754-46-7)
- 2-Pyrazinecarboxylic acid, 5-(fluoromethoxy)-, 1,1-dimethylethyl ester (CAS 1956318-53-8)
- 4-Methoxy-N-methyl-N-(trifluoromethyl)aniline (CAS 149143-94-2)
- 3',5'-Dimethyl-1'-(2-methylprop-2-en-1-yl)-1H,1'H-3,4'-bipyrazole-5-carboxylic acid (CAS 890624-75-6)
- (1-(tert-Butoxycarbonyl)-5-formyl-1H-indol-2-yl)boronic acid (CAS 913388-54-2)
- 6-Trifluoromethyl-benzothiazol-2-ylamine acetate (CAS 1951439-71-6)
- methyl 5-bromo-4-chloro-2-nitrobenzoate (CAS 1820703-50-1)
- 2-(2,3-Dihydroxyphenyl)-1,5-dimethyl-1H-pyrazol-3(2H)-one (CAS 64317-68-6)
- Pitavastatin Impurity 82 (CAS 782-01-4)
- 7-Fluoro-5-hydroxyindolin-2-one (CAS 1448460-10-3)
- 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]isoxazole (CAS 1314136-00-9)
- Delicious Peptide (bovine) (CAS 73984-05-1)
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