9-(2-Hydroxynaphthalen-1-yl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione CAS 180984-77-4
| CAS No. | 180984-77-4 |
| Molecular Formula | C27H28O4 |
| Molecular Weight | 416.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 9-(2-Hydroxynaphthalen-1-yl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione.
CATO supplies 9-(2-Hydroxynaphthalen-1-yl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione (CAS 180984-77-4), a certified reference material (molecular formula C27H28O4, MW 416.51 g/mol) for analytical method development and quality control.
Owing to a steroid core, a hydroxyl group, an ether linkage, 9-(2-Hydroxynaphthalen-1-yl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 416.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 9-(2-Hydroxynaphthalen-1-yl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H28O4 |
| Molecular Weight | 416.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
Related Hydroxynaphthalen Standards
- 2-((5-(3-Hydroxynaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-nitrophenyl)acetamide (CAS 332377-28-3)
- N'-((2-Hydroxynaphthalen-1-yl)methylene)-3-methyl-1-phenyl-1H-thieno[2,3-c]pyrazole-5-carbohydrazide (CAS 296262-01-6)
- N’-[(2-hydroxynaphthalen-1-yl)methylidene]-3-(naphthalen-2-yl)-1H-pyrazole-5-carbohydrazide (CAS 1310363-55-3)
- 2-((5-(3-Hydroxynaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-methyl-3-nitrophenyl)acetamide (CAS 332377-38-5)
- N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide (CAS 1105698-15-4)
- N-(2-(2-hydroxynaphthalen-1-yl)-4-methoxy-3,5-dimethylphenyl)-4-methylbenzenesulfonamide (CAS 1832514-29-0)
- 1,10-Bis(1-hydroxynaphthalen-2-yl)decane-1,10-dione (CAS 13379-63-0)
- (2E)-1-(1-Hydroxynaphthalen-2-yl)-3-[3-methoxy-4-(pyrrolidin-1-yl)phenyl]prop-2-en-1-one 1353224-57-3 (CAS 1353224-57-3)
Recommended Standards
- (2s,3As,6ar)-1-[(2r)-2-{[(2r)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid (CAS 1807941-03-2)
- Diethyl 2,2'-(1,3-phenylene)bis(4-methylthiazole-5-carboxylate) (CAS 1858241-92-5)
- Tetrakis(4-ethynylphenyl)methane (CAS 177991-01-4)
- Diethyl 2,2'-(1,3-phenylenebis(thiazole-2,4-diyl))diacetate (CAS 1858256-06-0)
- Ethyl 2,3-dimethylbut-2-enoate (CAS 13979-28-7)
- (1-(3-Fluorophenyl)-1h-tetrazol-5-yl)methanamine hydrochloride (CAS 1426291-28-2)
- N-(2-hydroxyethyl)-4-(pyrrolidin-1-yl)benzamide (CAS 952183-27-6)
- Ethosuximide impurity 10 (CAS CATO-C4X-262510)
- 3-Methyl-5-(methylthio)-1H-pyrazolo[4,3-e][1,2,4]triazine (CAS 497836-76-7)
- Methyl 6-iodobenzofuran-2-carboxylate (CAS 1300026-63-4)
- (E)-N'-(1-(2-(Cyclohexylmethoxy)-5-methylphenyl)-2,2,2-trifluoroethylidene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 2738683-38-8)
- 3-(Hydrazinylmethyl)pyridine hydrochloride (CAS 57616-01-0)
- 4-Bromo-6-(tert-butyl)-5-methoxy-2-methyl-2,3-dihydro-1H-inden-1-one (CAS 952516-23-3)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
Why CATO?
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