methyl 2-bromo-2-[2-(trifluoromethyl)phenyl]acetate CAS 181039-99-6
| CAS No. | 181039-99-6 |
| Molecular Formula | C10H8BrF3O2 |
| Molecular Weight | 297.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
methyl 2-bromo-2-[2-(trifluoromethyl)phenyl]acetate (CAS 181039-99-6) is a high-purity analytical reference standard with the molecular formula C10H8BrF3O2 and a molecular weight of 297.07 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, methyl 2-bromo-2-[2-(trifluoromethyl)phenyl]acetate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 297.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), methyl 2-bromo-2-[2-(trifluoromethyl)phenyl]acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8BrF3O2 |
| Molecular Weight | 297.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F/Br-containing |
Related methyl Standards
- Ethyl 3-bromo-5-(trifluoromethyl)benzoate (CAS 1018473-24-9)
- Methyl 2-(2-bromo-4-(trifluoromethyl)phenyl)acetate (CAS 1069115-04-3)
- Methyl 2-[2-Bromo-5-(trifluoromethyl)phenyl]acetate (CAS 1069115-16-7)
- Methyl 2-(4-bromo-3-(trifluoromethyl)phenyl)acetate (CAS 1159512-71-6)
- Ethyl 2-bromo-5-(trifluoromethyl)benzoate (CAS 1214336-55-6)
- Ethyl 3-bromo-2-(trifluoromethyl)benzoate (CAS 1214346-25-4)
- 4-Bromo-2-(trifluoromethyl)benzoic acid ethyl ester (CAS 1214378-94-5)
- Ethyl 3-bromo-4-(trifluoromethyl)benzoate (CAS 1214386-97-6)
Recommended Standards
- 2-Bromo-6-(3,3,3-trifluoropropyloxyl)benzaldehyde (CAS 1713160-79-2)
- 2-(3-Bromo-4-methyl-5-(trifluoromethyl)phenyl)acetic acid (CAS 2387022-29-7)
- Ethyl 2-(3-bromo-2-fluorophenyl)-2,2-difluoroacetate (CAS 1697770-93-6)
- 2-(5-Bromo-2-methyl-3-(trifluoromethyl)phenyl)acetic acid (CAS 2383520-58-7)
- (4-Fluorophenyl)(tetrahydrofuran-2-yl)methanamine (CAS 1016495-59-2)
- 3-(3-Aminophenyl)-1,3-oxazolidin-2-one (CAS 34232-43-4)
- 2-(Chloromethyl)-7-methoxy-1H-benzo[d]imidazole (CAS 405173-83-3)
- 2-((3,4-Difluorophenyl)thio)-N-(prop-2-yn-1-yl)acetamide (CAS 1197728-31-6)
- tert-Butyl 3-(propylamino)propanoate (CAS 701300-49-4)
- (E)-1-Allyl-2-(2-(furan-2-yl)vinyl)-1H-benzo[d]imidazole (CAS 637754-25-7)
- 2-chloro-6-(1H-pyrrol-1-yl)benzenecarbonitrile (CAS 418762-89-7)
- 2-((7-(3,4-Dimethoxyphenyl)quinoxalin-2-yl)amino)-N-methylacetamide (CAS 1513879-21-4)
- 4-((1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)phthalonitrile (CAS 906673-33-4)
- Lixisenatide (CAS 320367-13-3（free base）)
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