2-Fluoro-4-(thiazol-5-ylmethoxy)benzonitrile CAS 181040-44-8

Purity 97%+In StockPharmaceutical Standards
CAS No.181040-44-8
Molecular FormulaC11H7FN2OS
Molecular Weight234.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-4-(thiazol-5-ylmethoxy)benzonitrile CAS 181040-44-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Fluoro-4-(thiazol-5-ylmethoxy)benzonitrile.

CATO supplies 2-Fluoro-4-(thiazol-5-ylmethoxy)benzonitrile (CAS 181040-44-8), a certified reference material (molecular formula C11H7FN2OS, MW 234.25 g/mol) for analytical method development and quality control.

2-Fluoro-4-(thiazol-5-ylmethoxy)benzonitrile (C11H7FN2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Fluoro-4-(thiazol-5-ylmethoxy)benzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H7FN2OS
Molecular Weight234.25 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2008
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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