Trelagliptin Impurity 53 CAS 1812193-01-3
| CAS No. | 1812193-01-3 |
| Molecular Formula | C18H20FN5O2 |
| Molecular Weight | 357.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Trelagliptin Impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Trelagliptin Impurity 53 (CAS 1812193-01-3) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20FN5O2 and a molecular weight of 357.38 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Trelagliptin Impurity 53 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 357.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H20FN5O2 |
| Molecular Weight | 357.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Trelagliptin Standards
- Trelagliptin Impurity 22 (CAS 865759-25-7)
- Trelagliptin Impurity 4 (CAS 2206135-35-3)
- Trelagliptin Impurity 51 (CAS 2087874-93-7)
- Trelagliptin Impurity 61 (CAS 2514681-74-2)
- Trelagliptin impurity 81 (CAS CATO-C4X-104681)
- Trelagliptin impurity 87 (CAS 2270843-82-6)
- Trelagliptin Impurity 62 (CAS CATO-C4X-104662)
- Trelagliptin-13C-d3 (CAS 2707203-34-5)
Recommended Standards
- Capecitabine Impurity 48 (CAS CATO-C4X-102448)
- Axitinib Impurity 55 (CAS CATO-C4X-107155)
- Raltitrexed Impurity 11 (CAS 651295-42-0)
- Axitinib Impurity 77 (CAS CATO-C4X-107177)
- Vazegepant impurity 34 (CAS CATO-C4X-320034)
- Teprenone impurity 50 (CAS CATO-C4X-208150)
- Fasudil Impurity 39 (CAS 4403-78-5)
- (4S)-8-azaspiro[4.5]decan-4-ol;hydrochloride (CAS 2387561-22-8)
- 4-(1-((1-Phenyl-1H-1,2,4-triazol-3-yl)oxy)ethyl)pyrimidin-2-amine (CAS 320416-48-6)
- 4-Cyclohexylquinolin-2(1H)-one (CAS 197455-64-4)
- trans-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropanecarboxylic acid (CAS 1612892-47-3)
- 2,2,7-Trifluoro-4-(trifluoromethyl)benzofuran-3(2H)-one (CAS 2186640-42-4)
- 4-Methyl-5-[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]-4H-1,2,4-triazole-3-thiol (CAS 477709-23-2)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com